Parody Of . . .Edit
Mary Jane Watson. They also share the same hair-color (like Mary Jane Waterbuffalo).
Mary Crane Watsow has appeared in Amazing Spider-Man Family #4 and the Spider-Ham 25th Anniversary Special #1.
Mary Crane Watsow is an alternate, if not replacement, version of Mary Jane Waterbuffalo, an original Spider-Ham character. Neither have appeared since.